Founder of HRT University®
NICO
MISLEH,
MSN, FNP-C
Board-certified Family Nurse Practitioner. Founder of HRT University. Clinical educator to 3,000+ licensed providers globally.
Built in the Clinic. Taught from Practice.
Nico Misleh is an actively practicing board-certified Family Nurse Practitioner treating patients through Apollo Health Optimization, his direct-pay integrative medicine and HRT clinic in Cincinnati, Ohio. He is licensed across Ohio and Kentucky and sees patients via telehealth and virtual visits.
His clinical focus has been hormone optimization, testosterone replacement therapy, bioidentical hormone therapy, and integrative medicine for more than eight years. That is not a credential on paper. It is the foundation that every course module, every podcast episode, and every conference session is built on.
Everything he teaches at HRT University is grounded in what he does in practice. Not theory. Not abstraction. The same framework he uses in his own clinic with his own patients.
He built Apollo alongside his wife, Cherrell Misleh, BSN-RN, who co-founded and operates the practice. They run it the way medicine should be run: direct-pay, root-cause, unhurried.
Why He Built HRT University
Nico grew up in Cincinnati, homeschooled by a mother who rejected the conventional model of education in favor of something slower, deeper, and more deliberate. Learning was for its own sake. Curiosity was the point, not the test. That did not go away when he went into medicine. His maternal grandfather was a private-practice physician. Visiting his office as a child, Nico watched what medicine looked like when a clinician worked on his own terms: present with patients, accountable to the person in front of him rather than a billing code. That image stayed.
He trained at the University of Cincinnati and earned his MSN from Chamberlain University. He entered practice the conventional way. And he felt, fairly quickly, what most clinicians feel: the distance between what the guidelines say and what the patient in front of you is actually experiencing. He discovered functional and integrative medicine. He built a practice around it. He learned that hormones were not a niche, they were foundational, and that most providers were never taught how to actually work with them in any clinical depth.
He and Cherrell built Apollo Health Optimization to practice medicine the way it deserved to be practiced. Outside the insurance model. With time to think. With room to treat the root cause instead of managing the downstream effect. And then he kept watching colleagues struggle with the same questions he had once struggled with. Providers who cared deeply, practiced carefully, and still felt uncertain. Not because they lacked ability, but because they had never been given a real framework. HRT University launched in April 2025. Not to sell a course. To close a gap that had been costing patients the care they deserved.
Education Built Around Reasoning, Not Recipies
HRT University is a physiology-first clinical education platform for licensed healthcare providers. Nurse practitioners, physicians, PAs, pharmacists, RNs, and CNMs. It launched in April 2025 and has educated more than 3,000 providers globally in its first year.
The flagship product is the HRT Master Course. Six modules covering Metabolic Foundations, Male HRT, Female HRT, Advanced Female Endocrinology, Thyroid Optimization, and Adjunct Hormones. The course is not a protocol library. It is a reasoning framework: the kind of clinical clarity that holds up when a patient does not follow the script. Additional courses are in development, each built from the same physiology-first foundation.
THE MASTER COURSE
The Master Course is jointly accredited in partnership with Pinnacle Conference, LLC. Pinnacle is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), meaning course credit applies toward CME/CE for physicians, nurses, and pharmacists. Providers earn 30 CE hours, including 12 hours of pharmacology.
HRTU LIVE
HRTU Live is the annual conference. The inaugural edition was held in September 2025 in Covington, Kentucky. The second edition is scheduled for September 18 to 19, 2026, with a VIP day, two full conference days, 12 CE hours, and a Saturday evening reception.
THE PODCAST
Clinical education, business strategy, and provider interviews, released on a consistent schedule.
CONFERENCES & EVENTS
The Aesthetic Show Featured Speaker
Faculty, Integrative Aesthetics Symposium, Las Vegas. Solo presentation on Hormone Testing. Panelist, The Hormone Consult. Faculty, The Wellness Edit. Co-presented alongside Heather Hirsch MD, Raja Sivamani MD, and other leaders in integrative aesthetics.
A4M — American Academy of Anti-Aging Medicine Panelist
Multiple appearances. Featured speaker, Access Medical Lunch & Learn. A4M is one of the largest CME organizations in anti-aging, regenerative, and functional medicine, with a global physician and NP audience.
Silverback SummitFeatured Speaker
Speaker at Ali Gilbert’s premier men’s health event bridging fitness, medicine, and TRT for coaches and clinicians. Focus: testosterone optimization and the clinical model behind results-driven men’s health.
Injectable EDU
Two presentations. Custom provider reference guide developed for attendees: the Optimal Lab Reference Range.
The Elite NP Annual Conference
Guest speaker. ANCC-accredited conference for NP entrepreneurs building and scaling independent practices. Draws NP owners, multi-clinic operators, and nationally recognized educators.
The Elite NP Millionaire Conference
Guest speaker. Limited-seat, high-intensity event for established NP practice owners focused on wealth strategy and scaling. One of the most recognized stages in the NP entrepreneurship community.
Monarch Aesthetic Services
Guest speaker.
The Aesthetics Institute
Featured webinar presenter.
NICO LIVE 2025
Founder and principal speaker. Inaugural HRTU annual conference, Covington, KY, September 2025.
HRTU Live 2026
Founder and principal speaker. September 18-19, 2026. VIP day, two full conference days, 12 CE hours, Saturday evening reception.
PODCAST GUEST SPOTS
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Smart Nutrition Made Simple
Guest: hormones, depleted men, and what standard labs miss. Hosted by Benjamin Brown, Body Systems. -
Nurses Living the Good Life
Episode 130: Building an HRT and mental health practice. Hosted by Ann Konkoly. -
Business By The books
Two appearances, Episodes 148 and 246. Financial clarity, clinic scaling, and launching HRT University. Hosted by Danielle Hayden, Kickstart Accounting. -
Consider Cannabis
Cannabis, the endocannabinoid system, and NP education. -
Inertia Medicine
Interview with Dr. Jeremy Girmann: TRT, integrative medicine, neurosteroids, and longevity.
AS FEATURED IN
WCPO 9 NEWS
EIN PRESSWIRE
CANVASREBEL
VOYAGE OHIO
“Hormones influence nearly every system in the body. When you understand the ‘why’ behind the lab values, you transform from a prescriber into a clinician. It is a framework built on physiology, not fear.”
- NICO MISLEH
Ready to Build Your HRT Practice on a Foundation That Holds?
If you are a licensed provider who wants to stop piecing it together and start practicing with genuine clinical confidence, there are two ways to go deeper.