Clinical Education for Licensed Providers. Built on Physiology, Not Protocols.
HRT University provides physiology-based clinical education for licensed providers who want to practice hormone and metabolic medicine with clarity and confidence.
Struggling to feel confident with hormones?
Most clinicians were never formally trained in hormone therapy.
You learned fragments. Lab ranges. Isolated protocols. Opinions that conflict.
In practice, the questions are different. Symptoms that do not match labs.
Patients who do not respond as expected.
Tradeoffs between safety, dosing, and follow-up.
Hormones interacting with thyroid, insulin, cortisol, and sleep.
Confidence erodes when the framework is unclear.
HRT University exists to organize complexity so you can practice with steadiness.
How we teach
Hormone and metabolic medicine requires more than algorithms.
At HRT University™, Clinical Education for Licensed Providers is built around:
- Physiology over memorization
- Mechanisms before rigid rules
- Clinical reasoning before protocols
- Decisions you can explain and defend
This framework shapes every course, article, and live event we create.
The HRT University Master Course
Our foundational program for clinicians who want a structured framework for hormone therapy in men and women.
Inside the course you develop:
- Clinical reasoning for testosterone and female hormone therapy
- Pattern recognition in lab interpretation
- Dosing logic and follow-up strategy
- Risk framing and defensible documentation
The goal is not memorized protocols.
It is sound clinical judgment.
• Jointly Accredited • Includes 12 Pharmacology Hours
• ANCC Accredited • Includes 12 Pharmacology Hours
Current clinical thinking
Explore physiology-based education across key topics:
Testosterone therapy reasoning
Female hormone physiology
Progesterone patterns
Thyroid and metabolic context
This framework shapes every course, article, and live event we create.
OUR BLOGS

Podcast EP #106 | Benefits of Progesterone in Women and Men: Why the Uterus Was Never the Point
Progesterone got filed under women’s health. Then, inside women’s health, it got filed again, under the uterus. That second filing is the one that does the damage. If you’re prescribing

Podcast EP #105 | DHT Causes Hair Loss… Except When It Doesn’t
DHT causes hair loss, but the mechanism is more complex than most providers were taught. Dihydrotestosterone (DHT) can miniaturize hair follicles in genetically sensitive individuals, but it can also promote

Podcast EP #104 | Cortisol and Hormones: What the Physiology Actually Shows
You have a patient who should be better by now. Her estradiol is where you want it. Her progesterone is dosed. She still wakes at three in the morning, still
Podcast
Clinical conversations on hormones, clinical decision-making, and modern practice.
Live Clinical Education for Licensed Providers
The HRTU Conference brings providers together for physiology-based teaching and practical application.
Less performance. More reasoning.
Built by a practicing clinician
HRT University was created by Nico Misleh, MSN, FNP-C after seeing the gap between fragmented hormone education and real clinical demands.
HRTU is Jointly accredited in partnership with Pinnacle Conference, LLC.
Nico is 100% dedicated to helping you be successful. I appreciate such an amazing successful clinician who has an abundance mentality and wants to pay it forward! It is a rare find! This is a great business investment that will truly pay itself off in massive ways!

Sydney Arnold
APRN
Loving the passion behind the lectures – It’s clear that this course is built on a deep understanding of the subject.

Mike Belkin
APRN
I highly recommend Nico to anyone seeking to deepen their understanding of functional medicine, hormones, & weight loss management. It not only expanded my clinical knowledge but also inspired me to adopt a more integrative & patient-centered approach in my own practice.

Michelle Wolff
APRN
Nico is literally the best at what he does. Not only will you learn the foundation of hormones, functional medicine and clinic operational norms, but you will also learn from one of the most forward thinking practitioners in our country.

Nicole Waterhouse
APRN
Nico and HRT University are truly top-tier. The hormone optimization course he created is the most thorough, user-friendly resource I’ve found online. I highly recommend it to anyone serious about learning hormone optimization the right way.

Amy Melchior
APRN
You will NOT regret buying the Master Course! TAKE IT! GET IT! GRAB IT! YOU’LL LOVE IT! It is fundamental, yet precise and eloquent. You WILL DEFINITELY be able to treat immediately after you are done with Nico’s Master Course!

Christine Longo
APRN
Nico’s knowledge in both caring for patients and running a small business is invaluable to any provider just starting out or not sure how to navigate being out on their own.

Kelly Twells
APRN
Continue your education
Whether you prefer structured coursework, in-depth articles, live events, or ongoing conversation, HRT University is designed to support thoughtful clinical growth.